alpha-Biotin-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 10.000 Dalton) - Names and Identifiers
alpha-Biotin-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 10.000 Dalton) - Physico-chemical Properties
Molecular Formula | C22H34N4O8S
|
Molar Mass | 514.59236 |
Storage Condition | -20℃ |
alpha-Biotin-omega-carboxy succinimidyl ester poly(ethylene glycol) (PEG-MW 10.000 Dalton) - Introduction
Biotin-PEG-NHS(Biotin-PEG-NHS) is a compound that structurally contains a biotin group, a polyethylene glycol chain, and an active ester group.
Nature:
Biotin-PEG-NHS is a solid or powder, soluble in some organic solvents such as dimethyl sulfoxide and dimethylformamide.
Use:
Biotin-PEG-NHS are widely used in biochemistry and biomedicine. It is mainly used for the preparation of biotin-modified macromolecular compounds, such as biotin-modified proteins, peptides, antibodies and polymers. These biotin-modified compounds have important applications in drug delivery, protein and cell interaction studies, immunoassays and biosensors.
Preparation Method:
Biotin-PEG-NHS are generally obtained by reacting biotin with a polyethylene glycol coupling agent with an N-hydroxysuccinimide ester (NHS) terminus. The reaction can be carried out in solution and catalyzed by a base.
Safety Information:
The use of Biotin-PEG-NHS should follow the relevant laboratory safety procedures. It is generally safe for humans and the environment under appropriate operating conditions, but care must be taken to prevent contact with skin, eyes and inhalation. Wear appropriate personal protective equipment such as lab gloves and goggles during use. In case of any contact or inhalation, rinse thoroughly immediately and seek medical attention if necessary.
Last Update:2024-04-09 02:00:56